“SUPERPORE” was developed by applying “Triple pore structure” of APACERAM Type-AX to absorbable tricalcium phosphate ceramics.
Clinical studies has shown excellent bone regeneration and balanced absorption of SUPERPORE and bone tissue replacement.
Three types of products with various porosity (75 – 57%) and strength (compressive strength: 5-48 MPa) are available depending on applying position and intended use. Blocks and granules are available for each type.

Approved products, models and indications may differ from country to country.
Please contact us for detail.

Features of SUPERPORE

Main specification

Triple Pore Structure

SUPERPORE has triple pore structure that is suitable for bone regeneration as illustrated in APACERAM Type-AX.

Surface structure (SEM images)
Macro pores: 100～300μm,　
Interconnecting pores: 50～100μm,　
Micro pores: 0.5～10μm

Fast bone formation, absorption and bone replacement

Evaluation by short to long term implantation test in canines.※3

As a result, regeneration of the bone was achieved in both cortical bone and medullary cavity including anatomical shape.

SUPERPORE high porosity type blocks (porosity 75%, Ø4mm x 12mmL) were implanted in the femurs of the canines and extracted in 4, 8, 13 and 26 weeks. Samples stained by toluidine blue were prepared for observation. (Implantation test was executed in accordance to ISO10993 in the facility of GLP level.)

Product Line-up

Granules, blocks, and cylinder models are available.

Triple Pore Structure

Fast bone formation, absorption and bone replacement

SUPERPORE balanced type blocks (porosity 67%, Ø4mm x 12mmL) were implanted in the femurs of canines and extracted in 4 and 13 weeks. Samples stained by toluidine blue were prepared for observation. Implantation tests were executed in accordance to ISO10993 in the facility of GLP level.

Active bone formation was observed around the material in 4 weeks. Early stage of the bone formation was observed in the pores whileabsorption of the SUPERPORE (Balanced type) l and replacement of new bone tissues were observed immediately below the periosteum and at the interface of the medullary cavity.
In 13 weeks, bone formation continuing the host bone and absorption of the material were observed in the cortical area, while medullary cavity and adipose tissues were formed in the medullary cavity area.

Product Line-up

Granules, blocks, cylinder and wedge models are available.

β-TCP　with high mechanical strength (compressive strength 48MPa)

Triple pore structure suitable for bone regeneration (porosity 57%)

Well balanced bone formation and absorption of the material, regeneration of the bone tissue and fast bone formation

SUPERPORE high strength type blocks (porosity 57%, Ø4mm x 12mmL) were implanted in the femurs of the beagles and extracted in 26 and 52 weeks. Undecalcified samples stained by Hematoxylin and Eosin were prepared for observation. Implantation test was executed in accordance to ISO10993 in the facility of GLP level.

26 weeks after implantation：Bone formation continuing to host bone and absorption of the material and replacement by bone were observed in the cortical area. 52 weeks after implantation: The material was almost absorbed and replaced by bone. Bone regeneration was observed allover the implantation area including anatomical form.

Product Line-up

Granules, blocks, cylinder and wedge models are available.