Research Pellets

Developing bio-related businesses using hydroxyapatite

We handle general-purpose pellets and cell culture carriers using the bioceramic “hydroxyapatite”, which is composed of the same composition as human bone and is extremely biocompatible. The general-purpose pellet “Apatite Pellet” is used for each user’s research application, such as dental research, cell culture, and toothpaste research.

Distributor: Cosmo Bio Co., Ltd.

Product Overview

Product Name: Apatite Pellet (Unsterile)

These pellets are made by molding hydroxyapatite into squares and circles and sintering them. It can be used for cell culture, tooth models, toothbrushes, toothpaste studies, cariogenic bacteria adhesion experiments, albumin adsorption evaluation, laser ablation substrates, tooth adhesion evaluation, and apatite standards.

forte

• It is of the same quality as medical bone filling materials.
• It is a dense sintered material with a purity of 99% or more and a relative density of 99% or more.
• It can be sterilized at high temperatures and pressures by autoclave. (121°C, 20 minutes)
• Cells can be stained using common methods such as HE staining and toluidine blue staining.
• Surface hardness. The quality of surface roughness and texture is stable.

bibliography

Apatite Pellets

• azi Anisur Rahman, Michiko Nishimura, Seishi Matsumura, Omar M.M Rodis and Tsutomu Shimono: Inhibition of the adhesive ability of Streptococcus mutans on hydroxyapatite pellet using a toothbrush equipped with TiO2 semiconductor and solar panel, PEDIATRIC DENTAL JOURNAL 20(1), 16-21, 2010
• RK ANISUR, Michiko Nishimura, Takashi Oda, Naoyuki Kagaya: Effect of the number of brushing times of apatite pellets in Soladay 3 on the adhesion of Streptococcus mutans. Journal of Pediatric Dentistry. 46(2)： p201，2008
• Nahoko Miyake, Toru Sato, Yoshinobu Maki: Experimental study on the adsorption of bovine serum albumin on apatite surface by zeta potential. Journal of Dental Sciences.110(2): p105-109,2010
• Atsushi Yamagishi, Masanobu Wakasa, Kuniyuki Nakanishi: Interaction of Sodium Monofluorophosphate with Hydroxyapatite, Proceedings of the Inorganic Phosphorus Chemistry Symposium, p80-81, 2006
• Kazushi Oshino, Manabu Toi, Tadayuki Tokunaga, Manabu Hosiya, Koji Maeda: Effects of fluoride-containing dual-agent toothpaste on fluoride uptake and enamel remineralization in vitro.Journal of Oral Health.J Dent Hlth 54:2-8,2004